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At IMB, we explore the molecular biology of the nucleus with an overarching focus on gene regulation, epigenetics & genome stability

Schweiger Lab

Research  Publications  Biography 

Selected publications

2024

Krummeich J, Nardi L, Caliendo C, Aschauer D, Engelhardt V, Arlt A, Maier J, Bicker F, Kwiatkowski MD, Rolski K, Vincze K, Schneider R, Rumpel S, Gerber S, Schmeisser MJ and Schweiger S ( 2024 ) Premature cognitive decline in a mouse model of tuberous sclerosis. Aging Cell , e14318 Link

2023

Rücklé C*, Körtel N*, Basilicata MF, Busch A, Zhou Y, Hoch-Kraft P, Tretow K, Kielisch F, Bertin M, Pradhan M, Musheev M, Schweiger S, Niehrs C, Rausch O, Zarnack K, Keller Valsecchi CI and König J ( 2023 ) RNA stability controlled by m6A methylation contributes to X-to-autosome dosage compensation in mammals. Nat Struct Mol Biol , 30:1207-1215  (*indicates joint contribution)  Link

2020

Cooper A, Butto T*, Hammer N*, Jagannath S, Fend-Guella DL, Akhtar J, Radyushkin K, Lesage F, Winter J, Strand S, Roeper J, Zechner U# and Schweiger S# (2020) Inhibition of histone deacetylation rescues phenotype in a mouse model of Birk-Barel intellectual disability syndrome. Nat Commun, 11:480 Link

Wendelmuth M, Willam M, Todorov H, Radyushkin K, Gerber S and Schweiger S (2020) Dynamic longitudinal behavior in animals exposed to chronic social defeat. PLoS ONE, 15:e0235268 Link

2018

Arnoux I*, Willam M*, Griesche N*, Krummeich J, Watari H, Offermann N, Weber S, Narayan Dey P, Chen C, Monteiro O, Buettner S, Meyer K, Bano D, Radyushkin K, Langston R, Lambert JJ, Wanker E, Methner A, Krauss S#, Schweiger S# and Stroh A# (2018) Metformin reverses early cortical network dysfunction and behavior changes in Huntington's disease. eLife, 7:e38744 Link

Monteiro O, Chen C, Bingham R, Argyrou A, Buxton R, Pancevac Jönsson C, Jones E, Bridges A, Gatfield K, Krauß S, Lambert J, Langston R, Schweiger S and Uings I (2018) Pharmacological disruption of the MID1/α4 interaction reduces mutant Huntingtin levels in primary neuronal cultures. Neurosci Lett, 673:44–50 Link

2017

Deciphering Developmental Disorders Study (2017) Prevalence and architecture of de novo mutations in developmental disorders. Nature, 542:433–438 Link